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During recent years two primary types
2019-09-06
During recent years, two primary types of models have been applied for calculating various thermodynamic properties of amino DPH solutions, i.e. excess Gibbs energy (gE) models used numerously to describe the solubility of amino acid solutions, and equations of state (EOS) models appropriate to obtain density, vapor pressure, enthalpy, etc.
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Acknowledgements The present study was supported by the Medi
2019-09-05
Acknowledgements The present study was supported by the Medical Science and Technology Program of Zhejiang Province2014KYA228 (Zhijun Zhou), 2016KYA195 (Jie Li) and 2017KY714 (Qingqing Xia); Zhejiang Provincial Natural Science Foundation of ChinaQ17H120001 (Jie Li); and Scientific Research Project of Taizhou Science and Technology Bureau in Zhejiang Province1402ky22 (Lingmin Zhang).
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Introduction To detect exposure to and effects of
2019-09-04
Introduction To detect exposure to and effects of neuroactive pesticides in aquatic organisms, one widely used biomarker is cholinesterase (ChE) activity, which, among other possible functions, catalyzes the hydrolysis of the neurotransmitter CYT387 sulfate salt (ACh) in the cholinergic synapses of the central and peripheral nervous system of animals and occurs in many molecular forms (Talesa et al., 2002, Sturm et al., 2007).
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c-Met inhibitor STAR Methods Acknowledgments We thank Genev
2019-09-03
STAR★Methods Acknowledgments We thank Geneviève Almouzni, Sophie Polo, Ralph Scully, Wael Mansour, and Jeremy Stark for providing cell lines and Wolf Heyer, Haico van Attikum, Martijn Luijsterburg, and Brendan Price for helpful discussions.
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We neither observed changes in midazolam eCLmet
2019-09-02
We neither observed changes in midazolam eCLmet indicative of significant inhibition of CYP3A4/5 during both experiments, despite the in vitro evidence for CYP3A4/5 inhibition (Theile et al., 2017).
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Despite low respiratory rates in citrus fruit prolonged peri
2019-08-30
Despite low respiratory rates in citrus fruit, prolonged periods of storage may cause significant changes in the levels of organic acids (Echeverria and Valich, 1988).
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To identify and characterize new
2019-08-29
To identify and characterize new possible molecular targets, the mechanisms of various kinds of TCDD toxicities that occur by abnormal regulation in the downstream of AhR signals have been studied (Yoshioka et al., 2011).
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Endothelial mechanotransduction Apoptosis
2019-08-28
Endothelial mechanotransduction Apoptosis Death associated protein kinase Conclusion DAPK is localized to the Betulinic acid network, and promotes actomyosin contractility.
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Among the different factors that modulate
2019-08-27
Among the different factors that modulate Schwann cell biology, several studies pointed out the role played by neuroactive steroids, in particular progesterone (P4) and its derivatives dihydroprogesterone (DHP) and allopregnanolone (ALLO).
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Introduction Cyclin dependent kinases CDKs are a family of
2019-08-26
Introduction Cyclin dependent kinases (CDKs) are a family of proline-directed serine/threonine kinases with roles in regulation of crucial cellular processes such as Asunaprevir (BMS-650032) and transcription [1].
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TRAF and TRAF were initially identified as
2019-08-24
TRAF1 and TRAF2 were initially identified as tumor necrosis factor receptor 2 (TNRF2)-associated components, TRAF4 was overexpressed in breast carcinoma cells, whereas TRAF3, TRAF5 and TRAF6 were discovered by their interaction with specific domains in the cytoplasmic tails of trans-membrane receptor CD40 [63].
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In humans individual differences in prefrontal dopamine are
2019-08-23
In humans, individual differences in prefrontal dopamine are partially caused by the Val158Met single-nucleotide polymorphism on the catechol-O-methyltransferase gene (COMT).
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Programmed cellular death or apoptosis is a process
2019-08-22
Programmed cellular death or apoptosis is a process genetically controlled that plays an important role in cellular homeostasis, being an important defense mechanism to remove cells that have been infected, damaged or mutated (Smith and Smith, 2012, Wlodkowic et al., 2011).
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DNA end processing enzymes
2019-08-21
DNA end processing enzymes The simplest DSB is one that consists of two blunt DNA ends as these termini can be re-joined without processing.
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For any vector let and For let The information matrix
2019-08-20
For any vector , let , and . For , let The information matrix for the partial likelihood at Eq. (2.2) can be expressed as It is well known that P005091 under certain regularity conditions such as (A)–(D) in Andersen and Gill (1982), where and denote the maximum likelihood estimator from Eq. (2.2) and the true value of , respectively.
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