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Different types of environmentally induced antinociception h
2020-05-09
Different types of environmentally induced antinociception have been reported in a wide range of species (e.g., Behbehani, 1995, Bolles and Fanselow, 1980, Harris, 1996, Millan, 2002, Rodgers, 1995). According to Bolles and Fanselow (1980), fear and pain are independent and competing motivational sy
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While lowering the TID exposure of electronics is fairly
2020-05-09
While lowering the TID exposure of electronics is fairly straightforward, there are other HATU induced effects that are not as easily mitigated, especially with COTS components. Single Event Effects (SEE) occur when a high-energy particle strikes the active area of an integrated circuit, causing ch
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Due to the results of the
2020-05-09
Due to the results of the experiment we decided to deploy our cloud service infrastructure with two platform-independent servers instead of one or three. This decision was based on two factors: (a) the use of more than one server is useful to avoid a bottleneck in the system, and (b) using more than
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In conclusion this study provides
2020-05-09
In conclusion, this study provides the first investigation of role of ACC receptors in parasitic nematodes. While research using C. elegans to evaluate anthelmintic targets is an excellent tool to provide relevant information, research on similar targets in parasitic nematode can provide key informa
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br Disclosures br Acknowledgements This work was
2020-05-08
Disclosures Acknowledgements This work was supported by the Natural Science Foundation of China (No. 81560587); the Fok Ying-Tong Education Foundation of China (No. 151107), the basic ability promotion project for young and middle-aged teachers in Universities in Guangxi (No. 2018KY1146) and t
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Importantly MPO is not only a marker of
2020-05-08
Importantly, MPO is not only a marker of cardiovascular disease but also emerges as a critical mediator of vascular inflammatory disease: Liberated MPO binds to the endothelium in a leukocyte-independent manner, is subsequently taken up by the endothelium and transcytoses and accumulates in the sube
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MuRF and MuRF in http
2020-05-08
MuRF1 and MuRF3 in cooperation with the E2 ubiquitin-conjugating enzymes UbcH5a, -b, and -c were found to mediate degradation of myosin heavy chain β/slow (MHC β/slow) and MHC IIa via UPS, both, in vitro and in vivo [60]. Mice lacking both MuRF1 and MuRF3 developed skeletal muscle myopathy and hyper
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Several authors have been pursuing the aim of finding good
2020-05-08
Several authors have been pursuing the aim of finding good performing organic solvent compatible adsorbers useful in the context of API purification [[10], [11], [12], [13], 22, 23]. For sulfonate GTIs, scavenging nucleophilic resins [22, 23] or molecular imprinted polymers (MIPs) [10] have been exp
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Recent studies have shown arsenic could cause autophagic cel
2020-05-08
Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma 2-Palmitoylglycerol [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its related
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Doxycycline HCl The main variable of the study was whether t
2020-05-08
The main variable of the study was whether there was an association between the COMT Val158Met polymorphism and motor behavior. Additionally, it was investigated whether the effects of the COMT genotypes on the role played by tonic/phasic DA are associated with the stability/flexibility nature of th
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Although the control group and tinnitus
2020-05-08
Although the control group and tinnitus group do not significantly differ based on age, gender or hearing loss, a limitation of this study is that the control group is only group-matched, and not individually matched. Furthermore, we only tested hearing acuity in tinnitus patients via standard pure
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Renal injury by cisplatin has
2020-05-08
Renal injury by cisplatin has been associated with oxidative stress, inflammation, and apoptosis (Francescato et al., 2007, Iseri et al., 2007, Kiymaz et al., 2008, Ueki et al., 2012). Specifically, apoptosis is an important mode of cell death in cisplatin nephrotoxicity, and many studies including
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Although the presence of calcium in RHA
2020-05-08
Although the presence of calcium in RHA-P active site is confirmed by the homology modeling, some additional observations can be made following the metal depletion and reconstitution experiments performed on RHA-Phis. EDTA-treated RHA-Phis recovers its activity in the presence of divalent cations su
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MLN4924 We report our experience using conventional cytogene
2020-05-08
We report our experience using conventional cytogenetic analysis, FISH using EWSR1 break-apart probes, RT-PCR, and Sanger sequencing to detect characteristic translocations in a total of 32 patients with ES diagnosed at Texas Children\'s Hospital over a 5-year interval. Materials and methods R
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To understand the behavior of enzymes in ILs at
2020-05-08
To understand the behavior of enzymes in ILs at a molecular level, it is first desirable to dissolve enzymes in the solvents. For soluble catalysts, there are many relatively simple spectroscopic and other techniques for obtaining accurate information at a molecular level. Parker et al. [9] reported
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