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br Experimental br Results and discussions br Conclusions Su
2020-08-04
Experimental Results and discussions Conclusions Summarily, a ‘turn-on’ molecular probe RD2 with advanced selectivity toward DNA was developed by the incorporation of semilunar geometry through molecular complexity. The influence of the complex molecular architecture was established through
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Spermatogenesis is a complex process started at the early
2020-08-04
Spermatogenesis is a complex process started at the early stage of fetal development, and includes three main stages: mitosis, meiosis and spermiogenesis (). The gonocytes differentiate from PGC at E13.5 in mice. As already known, the gonocytes (fetal and neonatal germ cells) enter the primordial te
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DNMT is the dominating enzyme
2020-08-04
DNMT1is the dominating enzyme responsible for maintenance of the DNA methylation pattern and the primary enzyme responsible for copying methylation patterns following DNA replication (Moore et al., 2013). DNMT1 maintains the mitotic inheritance of the original methylation pattern in a cell lineage d
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LIG CT contains two BRCT domains
2020-08-04
LIG4-CT contains two BRCT domains and XIR in between. BRCT domain is shown to be a phosphopeptide binding module [30], [31]. ATM and DNA-PKcs are thought to phosphorylate a number of proteins, including histone H2AX, in response to DNA damage, phosphorylated H2AX or other protein might be a bait of
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br Experimental The compounds were synthesized at Department
2020-08-04
Experimental The compounds were synthesized at Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences & Pharmaceutical Industries, Future University, Cairo. Melting points (°C) were determined on Mettler FP80 melting point apparatus and are uncorrected. Microanalyses were perf
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br Acknowledgments This work was supported in part
2020-08-03
Acknowledgments This work was supported in part by the Japan Society for the Promotion of Science (JSPS) Grants-in-Aid for Scientific Research, KAKENHI; the Funding Program for Next Generation World-Leading Researchers, Grant No. LS081 (H.H.); Research Fellowships for Young Scientists (Y.O. and R
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Albiglutide a glucagon like peptide agonist GLP agonist for
2020-08-03
Albiglutide, a glucagon-like peptide-1 agonist (GLP-1 agonist) for the treatment of type 2 diabetes (marketed as Tanzeum and as Eperzan and the US and Europe, respectively), was one of the first HSA-peptide or protein fusion product to be approved for clinical use. Whereas the NS3694 mg of pharmacol
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The problem we now face is that the reports
2020-08-03
The problem we now face is that the reports/guidelines EPRI NP-5652/TR-106439 do not specifically incorporate the indirect COTS SW such as FPGA logic synthesis tools. They provide a well-defined process for dedication, but focus on commercial-grade (hardware) items, which directly compose safety-gra
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While Colwell P has been commonly used
2020-08-03
While Colwell P has been commonly used to determine plant-available P for many years, DGT P is developing into a promising technique which has been proven successful in fields fertilised with inorganic P (Mason et al., 2010), as well as more recently in pot experiments with OA (Six et al., 2014). Wh
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The lymphotoxin LT pathway is a
2020-08-03
The lymphotoxin (LT)-pathway is a critical mechanism by which fetal LTi regulate lymphoid organogenesis, such as lymph nodes and Peyer’s patches (PP), during development and polymorphisms in the genes encoding LTα are linked to several phenotypes that contribute to metabolic syndrome [25]. Fetal ILC
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br Results and discussions In general experimental analysis
2020-08-03
Results and discussions In general, experimental analysis is time consuming and expensive. Thus, In the present study, Taguchi design of experiments (DOE) was adopted to reduce the number of trials. To analyze the data, a High Level Analysis (HLA) is performed by averaging measured data for each
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Piceatannol a polyphenol compound derived from grapes
2020-08-03
Piceatannol, a polyphenol compound derived from grapes and wine shows great antioxidant activity to scavenge free radicals [3]. Lots of researches focus on the effects of piceatannol on cancer cells, like A549, a non-small cell lung cancer line shows piceatannol increases cell apoptosis by enhancing
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Based on the structural resemblance
2020-08-03
Based on the structural resemblance between PriL-CTD and cryptochromes, it was suggested that the ssDNA path found in the cryptochrome may represent the binding site of the DNA template of the primase and the flavin Triciribine dinucleotide (FAD) binding site in the cryptochrome, the position of th
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NVP-BSK805 Sequential silver nitrate staining and FISH has b
2020-08-03
Sequential silver nitrate staining and FISH has been used to study rDNA in several plant species (Hasterok and Maluszynska, 2000; Idziak and Hasterok, 2008). The conjugation of these two techniques for rDNA studies has the advantage of establishing the activity, location and number of rDNA loci. As
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The IC were measured at nM steroid which was
2020-08-03
The IC50 were measured at 1000 nM steroid (which was within the Km range) in the present study. However, the Schizandrin A neurosteroid concentrations could be much lower, as in the case of rat brain allopregnanolone concentration was around 1 ng/g (3 nM). In this regard, this possibly leads to nan
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