• Human testicular peritubular cells HTPCs are

  2024-11-13

  

  Human testicular peritubular Carbenicillin (HTPCs) are also the only human testicular cell type that can be isolated, cultured and studied in vitro (Albrecht et al., 2006, Mayerhofer, 2013). Results from recent studies indicate that their roles go beyond sperm transport and include immunological fu

• br Detection and possible treatments for prostate cancer PC

  2024-11-13

  

  Detection and possible treatments for prostate cancer PC can be diagnosed, by screening for prostate-specific antigen (PSA) and after diagnosis, treatments may include intense observation, radical prostatectomy, radiation, chemotherapy, hormone therapy or vaccination depending on the type and sta

• From an historical perspective ligands for GPCRs adrenaline

  2024-11-13

  

  From an historical perspective, ligands for GPCRs (adrenaline, serotonin, IRAK-1-4 Inhibitor I or morphine, to name a few) have been identified before their receptor counterparts, at a time when the concept of receptor itself was controversial [15]. Although many cognate receptors for endogenous lig

• Acknowledgments br Introduction Pulmonary fibrosis PF is

  2024-11-12

  

  Acknowledgments Introduction Pulmonary fibrosis (PF) is a chronic, fibrosing interstitial pneumonia and a crushing disease that occurs as a result of a variety of lung injuries, including auto-immune, tuberculosis and traumatic insult [1], [2]. PF is characterized by the accumulation of extracel

• Different antioxidants were described as useful

  2024-11-12

  

  Different antioxidants were described as useful biomarkers in monitoring response to treatment in human and veterinary medicine [33,65,66]. In the same line, Thiol and TAC also proved to be useful biomarkers in monitoring the post-ovariohysterectomy period in queens with pyometra, since antioxidants

• br Results A total of respondents

  2024-11-12

  

  Results A total of 126 respondents completed the survey (68.5% response rate), with at least 65% response rate from each of the four represented sectors (denominators represent the total constituent body of the organization or the total attendees of the meeting): PUC 24 out of 37 (65%), SPUNZA 33

• br Androgen interference with the action of arachidonic acid

  2024-11-12

  

  Androgen interference with the action of arachidonic S-Adenosylhomocysteine metabolites’ actions; the other side of the coin Arachidonic acid, being a polyunsaturated fatty acid present in the phospholipids of the membrane of cells, is highly abundant within the organism. It is mainly involved i

• Intracellular Signaling Cascades From ligand sensitization t

  2024-11-12

  

  Intracellular Signaling Cascades. From ligand sensitization to translation of genes, all cellular processes are dependent on the intracellular levels and activity of partners involved in the signaling pathway. These signaling events lead to critical post-translational modifications including phospho

• The importance of TARPs for AMPAR expression and

  2024-11-12

  

  The importance of TARPs for AMPAR expression and function was revealed initially in the cerebellum, where the lack of γ-2 in the mutant mice waggler and stargazer (stg/stg) was associated with a selective loss of AMPAR-mediated synaptic currents in cerebellar granule SU11274 (Chen et al., 2000; Has

• br Results br Discussion Many tumor cells

  2024-11-12

  

  Results Discussion Many tumor heme oxygenase rely on EAAs to provide fundamental building blocks for macromolecular biosynthesis because they cannot synthesize EAAs de novo (Hattori et al., 2017; Sheen et al., 2011). Therefore, they must use highly effective transporters to maximize EAA uptak

• It is well known that TCDD is the most potent

  2024-11-12

  

  It is well-known that TCDD is the most potent ligand of AhR and it regulates gene expression, such as CYP1A1, via activation of AhR (Mimura and Fujii-Kuriyama, 2003). Besides Tomblin et al. (2016) have recently shown that TCDD via AhR regulated L-type amino AXL1717 transporter 1 expression in MCF-7

• Introduction Epinephrine is an endocrine hormone

  2024-11-12

  

  Introduction Epinephrine is an endocrine hormone mainly produced by adrenal medulla in response to stress (Tank and Lee Wong, 2015). This catecholamine exerts various major physiological effects, concerning notably the cardiovascular system, the respiratory system and the endocrine system, through

• 81 5 br Results br Discussion Today

  2024-11-12

  

  Results Discussion Today, enzymes play important roles in various fields. A good assay for enzyme activity is of great value, especially when it has good specificity, sensitivity, reproducibility and economy. ADK is the first identified enzyme in the metabolic pathway of adenosine salvage [15,

• Tranexamic Acid br Actin at presynapses br

  2024-11-12

  

  Actin at presynapses Conclusion Thanks to the recent discovery of rings, hotspots and trails, axonal Tranexamic Acid is back in the spotlight. These are exiting times for neuronal cell biologists armed with constantly improving labeling and imaging techniques to observe, quantify and perturb t

• br Autophagy at the Synapse The

  2024-11-11

  

  Autophagy at the Synapse The synapse is a highly specialized neuronal compartment that forms the basic unit of communication between neurons. Communication relies on electrical signals that are propagated down the axon of the presynaptic neuron, where they trigger the quantal release of neurotran

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